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Three Antioxidants (ginko biloba, grade seed extract, and selenium) for Alzheimers Treatment

2008-03-06来源:
cklist of Treatments for Alzheimer's Disease

Part 3 of 8

3. Three Antioxidants: ginko biloba, selenium, grape seed extract. There are numerous antioxidants available to combat free radicals in the bloodstream of Alzheimer's patients. The best antioxidants are foods, such as blueberries. However, because of the expense and limitations on getting dietary antioxidants, the Alzheimer's patients may need to take supplements.

I give my mother ginko biloba extract, two 120 mg capsules per day. A neurologist informed me that ginko may be useful in the early stages of the disease. Based on this advice, I took her off ginko when she progressed to the moderate stages of the disease. However, once I realized that ginko's antioxidant properties would help Alzheimer's patients regardless of what stage they were in for the disease progression, then I put her back on the supplement.

At first I was skeptical that ginko biloba was doing any good. But two facts changed my mind. First, one of my mathematical analyst colleagues at the Tennessee Valley Authority told me that he takes ginko and found that it significantly improved his ability to concentrate. He does not suffer from Alzheimer's or any other disability, but ginko has a true beneficial effect for him.

Second, ginko affects the blood chemistry of the person taking the supplement. For example, ginko enhances the anticoagulation effects of the drug Coumadin (Warfarin). Because ginko affects the blood chemistry, we have reason to suspect it might impact the blood supplied to the brain of Alzheimer's disease. Evidence has not emerged as to whether ginko biloba can cross the blood-brain barrier that prevents certain chemicals in the blood from reaching the brain. However, ginko produces enough physical manifestations that we do not have to rely on the bogus concept of "if you think it works, then it works. If you don't think it works, then it won't."

Second, my mother takes 200 mcg/day of selenium. Selenium has a number of wonderful properties, but the most useful for Alzheimer's patients is its antioxidant property. writing in the May 23, 2005 issue of the magazine Nation's Restaurant News, nutritionist Mary Tabacchi writes " A diet full of antioxidants can help ward off oxidation, which weakens arterial, heart, skin, kidney and gastrointestinal tract cells. As a result, oxidation likely hastens the aging process and increases one's risk for autoimmune diseases, including arthritis, muscular dystrophy, lupus and Alzheimer's disease. Oxidation occurs when oxygen pulls electrons from electron-rich molecules, such as fatty acids. That sparks the creation of free radicals, which assault cellular and intracellular membranes. As a result, cells are damaged or destroyed and immune functions are inhibited. However, antioxidants can help strengthen and repair cells, making them less susceptible to disease.

Anthocyanin antioxidants--which often come in the crayon colors of bright blue, purple and red--are best known for combating cancer. They can be found in blueberries, blackberries, black raspberries, red cabbage, beets and eggplant skins--and they protect against heart disease to boot.

Plant-based Vitamin C helps to fortify skin and bones and plays a special role in holding cells together. And grain germs, nuts, olives and avocados are chock full of Vitamin E, which protects against heart disease and helps prevent scarring. Whole grains and meats are full of selenium, also a combatant of heart disease."

The December 1, 2004 issue of Better nutrition, in an article captioned "The Big 10: Top health News for 2004," reports that selenium has a positive synergistic effect when taken with (natural) Vitamin E, and thus the two should be taken simultaneously to maximize their antioxidant properties.

Third, Alzheimer's patients should consider taking grape seed extract, 100 mg/day. I had trouble finding out about antioxidant supplements from medical doctors. Apparently, in four years of medical school, doctors may take one course in nutrition, or they may skip the course and just get a 3-hour lecture on the subject. It turns out few doctors can speak authoritatively on which supplements offer the most antioxidant effect to remove free radical oxygen molecules from the blood stream. Through independent research, I discovered that grape seed extract was thought to be even more potent as an